ILLUMINATE study of INCIVEK; high viral cure rate achieved with a 24-week INCIVEK combination regimen (50.55 +0.34)
Co announced that the New England Journal of Medicine (NEJM) published data from a Phase 3 study of INCIVEK(TM) (telaprevir) tablets in people with genotype 1 chronic hepatitis C who were new to treatment. In ILLUMINATE, INCIVEK (in-SEE-veck) was given for the first 12 weeks in combination with…
ContinueAdded by ken flagg on September 14, 2011 at 11:39pm — No Comments
Futures are slightly higher (S&P futures +2 vs. fair value; DJ futures +30), but are likely to see volatility around the release of the June Employment Report at 8:30 ET. Expectations are that Nonfarm Payrolls will increase by 80K and that the Unemployment Rate will remain at 9.1%. Yesterday's better-than-expected ADP report bolstered expectations for today's data and the S&P is now up 6.7% over the past eight trading sessions, so even a good employment…
ContinueAdded by ken flagg on July 8, 2011 at 11:13am — No Comments
U.S. equity futures are showing modest gains this morning, with S&P futures +5 vs. fair value and DJ futures +32. The strength follows a mixed performance in overseas markets, with most Asian markets closing with losses while the major European are higher at their mid-day. Asian markets were under pressure in response to yesterday's Chinese rate hike (Nikkei -0.1%, Hang Seng -1.0%, Shanghai Comp -0.6%). In Europe, stocks are higher (FTSE +0.4%, DAX +0.4%,…
ContinueAdded by ken flagg on July 7, 2011 at 8:30am — No Comments
Added by ken flagg on June 23, 2011 at 7:08am — No Comments
That has the major equity averages sporting gains in excess of 1%... News that China's PPI increased by 6.8% in May, as it did for the same period one year ago, and its CPI increased by a relatively in-line 5.5% were considered positives. The country also posted strong industrial production and retail sales figures, which were generally consistent with what was reported the year before. The decision by the country's central bank to raise the reserve requirement…
ContinueAdded by ken flagg on June 14, 2011 at 6:33pm — No Comments
Yesterday the major equity averages fell 2.3% and closed at their lows, after weaker-than-expected ADP employment data and ISM data sparked a broad-based selloff. Futures are trading around the flat line this morning (S&P futures flat vs. fair value, DJ futures flat), with more data on tap and as retailers report relatively disappointing May Same Store Sales results.
Overseas markets opened lower on the heels…
ContinueAdded by ken flagg on June 2, 2011 at 12:15pm — No Comments
After a strong performance yesterday, equity futures are trading just below the flat line this morning with S&P futures -1 vs. fair value and DJ futures -12. This follows a relatively flat session in overseas markets, with modest declines across Europe at mid-day (FTSE -0.2%, DAX -0.1%, CAC -0.1%) following a mixed day in Asia (Hang Seng -0.2%, Shanghai unchanged, Nikkei +0.3%). Manufacturing PMI data in Europe and China came in weaker than expected,…
ContinueAdded by ken flagg on June 1, 2011 at 1:13pm — No Comments
Added by ken flagg on June 1, 2011 at 12:05pm — No Comments
Added by ken flagg on April 7, 2011 at 9:14am — No Comments
Equity futures are trading just below the flat line this morning (S&P futures -2.5 vs. fair value, DJ futures -18), with modest weakness in overseas markets as the situation in Egypt deteriorates. The modestly lower futures trading comes on a stronger dollar (DXY is +0.269 at 77.360), and precedes a busy end of the week in terms of economic data. Specifically, we'll get…
ContinueAdded by ken flagg on February 3, 2011 at 9:30am — No Comments
Added by ken flagg on January 28, 2011 at 7:13pm — No Comments
Added by ken flagg on January 27, 2011 at 9:31am — No Comments
Added by ken flagg on January 20, 2011 at 2:42pm — No Comments
Co announced today that a pivotal Phase III trial of the investigational Janus kinase (JAK) inhibitor INC424 (also known as INCB018424 and INCB18424) has met its primary endpoint of significantly reducing spleen volume in patients with myelofibrosis. The study, called COMFORT-1 (COntrolled MyeloFibrosis Study with Oral JAK Inhibitor Therapy), showed treatment with INC424 provided a statistically significant reduction in spleen size in patients with…
ContinueAdded by ken flagg on December 20, 2010 at 8:02pm — No Comments
Futures have just given up a portion of their early bid after FDX earnings/guidance disappointed (S&P futures are now +1.5 vs. fair value; DJ futures are +24). FDX is down about 3% after missing on the top and bottom line and guiding in-line. The company cited "compensation and benefits headwinds" as it reinstated programs curtailed during the recession, along with more normalized growth in FedEx International Priority shipments and higher fuel…
ContinueAdded by ken flagg on December 16, 2010 at 9:53am — No Comments
Futures have just given up a portion of their early bid after FDX earnings/guidance disappointed (S&P futures are now +1.5 vs. fair value; DJ futures are +24). FDX is down about 3% after missing on the top and bottom line and guiding in-line. The company cited "compensation and benefits headwinds" as it reinstated programs curtailed during the recession, along with…
ContinueAdded by ken flagg on December 16, 2010 at 9:50am — No Comments
Moody's put Spain 's Aa1 rating on review for a potential downgrade, which fueled the worries in Europe again. This, coupled with a drop in business confidence in Japan as evidenced in the BOJ's Tankan Survey, has created negative sentiment across the markets. The Asian markets initially opened lower in reaction to the Tankan data, began to recover, but jerked lower (the Hang Seng in particular) when the news on Spain came out. The weaker yen most likely…
ContinueAdded by ken flagg on December 15, 2010 at 11:29am — No Comments
It appears the world markets are content to sit tight as narrow ranges are being seen across the board before the releases of key US data points and the ever important FOMC release. The Asian markets finished up slightly, and the European markets are relatively flat. There were some global data points worth pointing out overnight. Japan revised its Industrial Production and Capacity Utilization down from its initial October reading. The UK saw CPI…
ContinueAdded by ken flagg on December 14, 2010 at 9:53am — No Comments
Monday, December 13, 2010 8:13 AM
The world markets are seeing gains across the board as the much anticipated (and perhaps feared) benchmark rate hike in China never came to pass. This came despite the much stronger than anticipated CPI and PPI data that came out on Saturday. One wonders how stable these gains will be in the coming days now that inflation is at a 28 month high. You can expect…
Added by ken flagg on December 13, 2010 at 9:30am — No Comments
Co announced results from new analyses comparing XGEVA, the first new treatment for advanced cancer patients with bone metastases in nearly a decade to prevent skeletal-related events, to Zometa. "These results underscore the efficacy profile of XGEVA in preventing skeletal-related events (SREs) in patients with bone metastases from advanced breast cancer, as well as explore XGEVA's impact on pain and quality of life outcomes, compared to…
ContinueAdded by ken flagg on December 11, 2010 at 1:08pm — No Comments
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